Bong da 24h
trực tiếp Lễ trao giải thưởng "Quả bóng tiến thưởng 2021": Pedri nhấn giải "Cầu thủ trẻ em hay nhất 2021"
Dừng
| Cadiz | 1 - 4 | Atletico |
| Real Madrid | 2 - 1 | Sevilla |
| Roma | 1 - 0 | Torino |
| Napoli | 4 - 0 | Lazio |
| Marseille | 1 - 0 | Troyes |
| Como | 1 - 1 | Parma |
| Gent | 3 - 1 | Standard Liege |
| Sporting | 2 - 0 | Tondela |
| Atletico MG | 2 - 1 | Fluminense |
| Corinthians | 1 - 0 | Athletico Paranaense |
| Rosario Central | 2 - 2 | River Plate |
| Royal Antwerp | 3 - 0 | Oostende |
| Royal Antwerp FC | 03:00 | Oostende |
| FC Porto | 2 - 1 | Vitoria de Guimaraes |
| Club Atletico Platense | 04:00 | Huracan |
| Internacional | 1 - 1 | Santos FC |
| Argentinos Juniors | 3 - 0 | Gimnasia LP |
| Defensa y Justicia | 1 - 1 | Colon |
| CSKA Moscow | 0 - 2 | St. Petersburg |
| Tenerife | 2 - 0 | Real Sociedad B |
| Avai FC | 2 - 1 | Sampaio Correa |
| Botafogo RJ | 2 - 2 | Guarani |
| CS Alagoano | 4 - 0 | Brasil de Pelotas |
| Goias | 2 - 2 | Brusque |
| Londrina EC | 3 - 0 | Vasco domain authority Gama |
| Operario Ferroviario | 2 - 1 | CRB |
| Remo | 0 - 0 | Confianca |
| Vitoria | 0 - 1 | Vila Nova |
| RWD Molenbeek | 2 - 2 | Deinze |
| Vitesse | 0 - 0 | AZ Alkmaar |
| Academica | 3 - 0 | Sporting Covilha |
| FC Ufa | 1 - 1 | Spartak Moscow |
| Arsenal Tula | 3 - 1 | Lokomotiv |
| Brann | 0 - 1 | Molde |
| Colo Colo | 0 - 1 | Union Espanola |
| Curico Unido | 1 - 1 | Palestino |
| Universidad Catolica | 2 - 0 | Huachipato |
| Union La Calera | 1 - 2 | La Serena |
| Borneo FC | 2 - 1 | Persija Jakarta |
| LD Alajuelense | 3 - 0 | Municipal Perez Zeledon |
| Sporting San Jose | 0 - 2 | Club sport Herediano |
| C.S. Cartagines | 4 - 0 | ADR Jicaral |
| Guadalupe FC | 0 - 5 | Santos de Guapiles |
| Guanacasteca | 1 - 0 | Deportivo Saprissa |
| Deportivo Achuapa | 0 - 1 | Club Xelaju |
| Ludogorets | 2 - 0 | PFC CSKA-Sofia |
| Alashkert FC | 21:00 | Ararat |
| FC Alashkert | 21:00 | Ararat |
| Pyunik II | 1 - 1 | FC Alashkert II |
| AEL Limassol | 0 - 2 | Larnaca |
| Anorthosis | 1 - 1 | Apollon Limassol |
| Sparta Prague | 2 - 1 | Slovan Liberec |
| FC Kolos Kovalivka | 1 - 0 | Veres Rivne |
| FC Avanhard Kramatorsk | 0 - 2 | Alians |
| FC Obolon Kiev | 1 - 2 | Metalist Kharkiv |
| AaB | 1 - 3 | FC Copenhagen |
| FC Samgurali Tskhaltubo | 0 - 3 | Dinamo Batumi |
| FC Shukura Kobuleti | 1 - 2 | Saburtalo |
| Mezokovesd SE | 0 - 3 | Ferencvaros |
| Mura | 3 - 1 | Maribor |
| Novi Pazar | 2 - 0 | Proleter |
| Vojvodina | 3 - 1 | Mladost Lucani |
| FK Mladost Novi Sad | 1 - 1 | FK IMT Beograd |
| CS Universitatea Craiova | 2 - 3 | FC FCSB |
| Gaz Metan Medias | 1 - 1 | FCV Farul Constanta |
| Widzew Lodz | 3 - 2 | Zaglebie Sosnowiec |
| PAOK FC | 0 - 1 | Aris |
| Panathinaikos | 2 - 0 | Panetolikos |
| FK Qabala | 0 - 0 | Qarabag |
